2 papers
q-bio.TO2025
Integrating computational detection and experimental validation for rapid GFRAL-specific antibody discovery
Maria Francesca Abbate, Pierre Toxe, Nicolas Maestrali +5
The identification and validation of therapeutic antibodies is critical for developing effective treatments for many diseases. We present a computational approach for identifying a…
q-bio.PE2023
Computational detection of antigen specific B cell receptors following immunization
Maria Francesca Abbate, Thomas Dupic, Emmanuelle Vigne +3
B cell receptors (BCRs) play a crucial role in recognizing and fighting foreign antigens. High-throughput sequencing enables in-depth sampling of the BCRs repertoire after immuniza…