68 citations · 81 across the 12 of their papers we have counts for
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stat.AP2022
A flexible model-based framework for robust estimation of mutational signatures
Ragnhild Laursen, Lasse Maretty, Asger Hobolth
Somatic mutations in cancer can be viewed as a mixture distribution of several mutational signatures, which can be inferred using non-negative matrix factorization (NMF). Mutationa…
stat.ME2022
Model selection and robust inference of mutational signatures using Negative Binomial non-negative matrix factorization
Marta Pelizzola, Ragnhild Laursen, Asger Hobolth
The spectrum of mutations in a collection of cancer genomes can be described by a mixture of a few mutational signatures. The mutational signatures can be found using non-negative…