2 papers
q-bio.BM2026
Dark energy: the cost of function in protein evolution
Ezequiel A. Galpern, Federico Caamaño, Ignacio E. Sánchez +1
The evolutionary fate of proteins is driven by both folding stability and biological function, dual constraints that often conflict, creating frustration and imposing functional co…
q-bio.BM2025
Predicting protein folding dynamics using sequence information
Ezequiel A. Galpern, Federico Caamaño, Diego U. Ferreiro
Natural protein sequences somehow encode the structural forms that these molecules adopt. Recent developments in structure-prediction are agnostic to the mechanisms by which protei…