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20052026
most citedSingle-particle cryo-electron microscopy: Mathematical theory, computational challenges, and opportunities

148 citations · 1.2k across the 75 of their papers we have counts for

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Showing 2018Show all

5 papers · 1 filter

eess.IV2018★ 3 cited

Heterogeneous multireference alignment for images with application to 2-D classification in single particle reconstruction

Chao Ma, Tamir Bendory, Nicolas Boumal +2

Motivated by the task of 2-D classification in single particle reconstruction by cryo-electron microscopy (cryo-EM), we consider the problem of heterogeneous multireference alignme…

cs.IT2018

Toward single particle reconstruction without particle picking: Breaking the detection limit

Tamir Bendory, Nicolas Boumal, William Leeb +2

Single-particle cryo-electron microscopy (cryo-EM) has recently joined X-ray crystallography and NMR spectroscopy as a high-resolution structural method to resolve biological macro…

physics.comp-ph2018

Mathematics for cryo-electron microscopy

Amit Singer

Single-particle cryo-electron microscopy (cryo-EM) has recently joined X-ray crystallography and NMR spectroscopy as a high-resolution structural method for biological macromolecul…

cs.CV2018

APPLE Picker: Automatic Particle Picking, a Low-Effort Cryo-EM Framework

Ayelet Heimowitz, Joakim Andén, Amit Singer

Particle picking is a crucial first step in the computational pipeline of single-particle cryo-electron microscopy (cryo-EM). Selecting particles from the micrographs is difficult…

cs.IT2018

Estimation in the group action channel

Emmanuel Abbe, João M. Pereira, Amit Singer

We analyze the problem of estimating a signal from multiple measurements on a $\mbox{group action channel}$ that linearly transforms a signal by a random group action followed by a…