102 citations · 142 across the 6 of their papers we have counts for
6 papers
Stable developmental patterns of gene expression without morphogen gradients
Maciej Majka, Nils B. Becker, Pieter Rein ten Wolde +2
Gene expression patterns (GEPs) are established by cross-regulating target genes that interpret morphogen gradients. However, as development progresses, morphogen activity is reduc…
Stability of pattern formation in systems with dynamic source regions
M. Majka, R. D. J. G. Ho, M. Zagorski
We explain the principles of gene expression pattern stabilization in systems of interacting, diffusible morphogens, with dynamically established source regions. Using a reaction-d…
Edge usage, motifs and regulatory logic for cell cycling genetic networks
M. Zagorski, A. Krzywicki, O. C. Martin
The cell cycle is a tightly controlled process, yet its underlying genetic network shows marked differences across species. Which of the associated structural features follow solel…
Motifs emerge from function in model gene regulatory networks
Z. Burda, A. Krzywicki, O. C. Martin +1
Gene regulatory networks arise in all living cells, allowing the control of gene expression patterns. The study of their topology has revealed that certain subgraphs of interaction…
Distribution of essential interactions in model gene regulatory networks under mutation-selection balance
Z. Burda, A. Krzywicki, O. C. Martin +1
Gene regulatory networks typically have low in-degrees, whereby any given gene is regulated by few of the genes in the network. They also tend to have broad distributions for the o…
Sparse essential interactions in model networks of gene regulation
Z. Burda, A. Krzywicki, O. C. Martin +1
Gene regulatory networks typically have low in-degrees, whereby any given gene is regulated by few of the genes in the network. What mechanisms might be responsible for these low i…