11 citations · 19 across the 5 of their papers we have counts for
5 papers
Relaxing the aquaporin crystal structure in a membrane with surface vibrational spectroscopy
L. Schmüser, M. Trefz, S. J. Roeters +7
High-resolution structural information on membrane proteins is essential for understanding cell biology and for structure-based design of new medical drugs and drug delivery strate…
The hydrophobic effect characterises the thermodynamic signature of amyloid fibril growth
Erik van Dijk, Juami Hermine Mariama van Gils, Alessia Peduzzo +6
Many proteins have the potential to aggregate into amyloid fibrils, which are associated with a wide range of human disorders including Alzheimer's and Parkinson's disease. In cont…
Glucagon stop-go kinetics supports a monomer-trimer fibrillation model
Andrej Kosmrlj, Pia Cordsen, Anders Kyrsting +3
We investigate in vitro fibrillation kinetics of the hormone peptide glucagon at various concentrations using confocal microscopy and determine the glucagon fibril persistence leng…
Quality Control System Response to Stochastic Growth of Amyloid Fibrils
Simone Pigolotti, Ludvig Lizana, Daniel Otzen +1
We introduce a stochastic model describing aggregation of misfolded proteins and degradation by the protein quality control system in a single cell. In analogy with existing litera…
Stop-and-go kinetics in amyloid fibrillation
Jesper Fonslet, Christian Beyschau Andersen, Sandeep Krishna +6
Many human diseases are associated with protein aggregation and fibrillation. We present experiments on in vitro glucagon fibrillation using total internal reflection fluorescence…