1 citations · 1 across the 4 of their papers we have counts for
4 papers
Cell Division Changes Fate Decisions in a Genetic Toggle Switch
Charli Austin, Nikola Popovic, Ramon Grima
Gene regulatory networks govern cellular fate decisions through multistable dynamics. The genetic toggle switch is a canonical model of such behaviour; yet, the impact of cell divi…
Universal deterministic patterns in stochastic count data
Zhixing Cao, Yiling Wang, Ramon Grima
We report the existence of deterministic patterns in plots showing the relationship between the mean and the Fano factor (ratio of variance and mean) of stochastic count data. Thes…
Analysis of a detailed multi-stage model of stochastic gene expression using queueing theory and model reduction
Muhan Ma, Juraj Szavits-Nossan, Abhyudai Singh +1
We introduce a biologically detailed, stochastic model of gene expression describing the multiple rate-limiting steps of transcription, nuclear pre-mRNA processing, nuclear mRNA ex…
Investigating the robustness of the classical enzyme kinetic equations in small intracellular compartments
Ramon Grima
Classical descriptions of enzyme kinetics ignore the physical nature of the intracellular environment. Main implicit assumptions behind such approaches are that reactions occur in…