200 citations · 644 across the 18 of their papers we have counts for
3 papers · 1 filter
A Mathematical Programming Approach to the Fractionation Problem in Chemoradiotherapy
Ehsan Salari, Jan Unkelbach, Thomas Bortfeld
In concurrent chemoradiotherapy, chemotherapeutic agents are administered during the course of radiotherapy to enhance the primary tumor control. However, that often comes at the e…
Optimization of Radiation Therapy Fractionation Schedules in the Presence of Tumor Repopulation
Thomas Bortfeld, Jagdish Ramakrishnan, John N. Tsitsiklis +1
We analyze the effect of tumor repopulation on optimal dose delivery in radiation therapy. We are primarily motivated by accelerated tumor repopulation towards the end of radiation…
Exploiting tumor shrinkage through temporal optimization of radiotherapy
Jan Unkelbach, David Craft, Theodore Hong +5
In multi-stage radiotherapy, a patient is treated in several stages separated by weeks or months. This regimen has been motivated mostly by radiobiological considerations, but also…