3 papers
q-bio.QM2025
Nucleation feedback can drive establishment and maintenance of biased microtubule polarity in neurites
Hannah G. Scanlon, Gibarni Mahata, Anna C. Nelson +3
The microtubule cytoskeleton is comprised of dynamic, polarized filaments that facilitate transport within the cell. Polarized microtubule arrays are key to facilitating cargo tran…
cs.LG2025
Enhancing generalizability of model discovery across parameter space with multi-experiment equation learning (ME-EQL)
Maria-Veronica Ciocanel, John T. Nardini, Kevin B. Flores +3
Agent-based modeling (ABM) is a powerful tool for understanding self-organizing biological systems, but it is computationally intensive and often not analytically tractable. Equati…
physics.bio-ph2025
Emergent microtubule properties in a model of filament turnover and nucleation
Anna C. Nelson, Scott A. McKinley, Melissa M. Rolls +1
Microtubules (MTs) are dynamic protein filaments essential for intracellular organization and transport, particularly in long-lived cells such as neurons. The plus and minus ends o…