3 papers
q-bio.QM2025
Nucleation feedback can drive establishment and maintenance of biased microtubule polarity in neurites
Hannah G. Scanlon, Gibarni Mahata, Anna C. Nelson +3
The microtubule cytoskeleton is comprised of dynamic, polarized filaments that facilitate transport within the cell. Polarized microtubule arrays are key to facilitating cargo tran…
physics.bio-ph2025
Emergent microtubule properties in a model of filament turnover and nucleation
Anna C. Nelson, Scott A. McKinley, Melissa M. Rolls +1
Microtubules (MTs) are dynamic protein filaments essential for intracellular organization and transport, particularly in long-lived cells such as neurons. The plus and minus ends o…
math.DS2023
Minimal Mechanisms of Microtubule Length Regulation in Living Cells
Anna C Nelson, Melissa M Rolls, Maria-Veronica Ciocanel +1
The microtubule cytoskeleton is responsible for sustained, long-range intracellular transport of mRNAs, proteins, and organelles in neurons. Neuronal microtubules must be stable en…