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cs.LG2026
InstructPro2: Natural Language and Biological Grounding Guided De Novo Protein Design
Charles Novak, Zhenqiao Song, Chuan Li +2
The ability to generate proteins with desired functions is a central goal of computational biology. Although natural language can express diverse design objectives, existing protei…
cs.AI2026
Joint Discrete and SE(3) Diffusion for Protein Interface Design
Zhenqiao Song, Jianwen Xie, Lei Li
The design of high-affinity, target-specific protein binders is central to the development of modern therapeutics. However, existing protein-generation methods remain limited in th…