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q-bio.CB2024
Phenotype structuring in collective cell migration:a tutorial of mathematical models and methods
Tommaso Lorenzi, Kevin J Painter, Chiara Villa
Populations are heterogeneous, deviating in numerous ways. Phenotypic diversity refers to the range of traits or characteristics across a population, where for cells this could be…
q-bio.CB2024
Phenotypic switching mechanisms determine the structure of cell migration into extracellular matrix under the `go-or-grow' hypothesis
Rebecca M. Crossley, Kevin J. Painter, Tommaso Lorenzi +2
A fundamental feature of collective cell migration is phenotypic heterogeneity which, for example, influences tumour progression and relapse. While current mathematical models ofte…