5 papers · 1 filter
A mathematical model for irreversible damage of the collagen scaffold in the myocardium
Irena Radišić, Francesco Regazzoni, Luca Dede' +1
We propose a dissipative, irreversible damage model for anisotropic media in large deformations to address the damage process of the myocardium following a cardiac infarction. We m…
The functional impact of myofiber macroscopic organization and disarray in computational models of the murine heart
Carlo Guastamacchia, Roberto Piersanti, Francesco Giardini +5
A major challenge in computational models of cardiac electromechanics is the reconstruction of myocardial fiber architecture, as direct in vivo measurements of fiber orientation ar…
Coupling models of resistive valves to muscle mechanics in cardiac fluid-structure interaction simulations
Michele Bucelli, Luca Dede'
To accurately simulate all phases of the cardiac cycle, computational models of hemodynamics in heart chambers need to include a sufficiently faithful model of cardiac valves. This…
Influence of cellular mechano-calcium feedback in numerical models of cardiac electromechanics
Irena Radišić, Francesco Regazzoni, Michele Bucelli +3
Multiphysics and multiscale mathematical models enable the non-invasive study of cardiac function. These models often rely on simplifying assumptions that neglect certain biophysic…
Coupled Eikonal problems to model cardiac reentries in Purkinje network and myocardium
Samuele Brunati, Michele Bucelli, Roberto Piersanti +2
We propose a novel partitioned scheme based on Eikonal equations to model the coupled propagation of the electrical signal in the His-Purkinje system and in the myocardium for card…