activity
20222026
most citedMultimodal Imaging-based Material Mass Density Estimation for Proton Therapy Using Physics-Constrained Deep Learning

16 citations · 31 across the 10 of their papers we have counts for

collaborators

11 papers

physics.med-ph2026

One-for-All Adaptive Radiotherapy Planning Agent: A Foundation Framework for Daily CBCT-guided Radiotherapy

Shaoyan Pan, Kirk Jon Luca, Yuan Gao +8

In this work, we introduce the One-for-All Adaptive Radiotherapy Planning Agent, a unified foundation-model-based system that performs complete, treatment-specific online adaptive…

cs.CV2026

SAFE-Diff: Scale-Aware Attention and Feature-Dispersive Diffusion with Uncertainty Estimation for Contrast-Enhanced Breast MRI Synthesis

Tianyu Zhang, Xinglong Liang, Jarek van Dijk +13

Synthesizing high fidelity contrast enhanced MRI is clinically valuable for safer and more efficient breast cancer screening, yet remains challenging due to complex lesion textures…

cs.CV2026

Universal CT Representations from Anatomy to Disease Phenotype through Agglomerative Pretraining

Yuheng Li, Yuan Gao, Haoyu Dong +5

Computed tomography (CT) is a central to three-dimensional medical imaging, yet CT-based artificial intelligence remains fragmented across task-specific models for segmentation, cl…

cs.CV2025

Limited-Angle CBCT Reconstruction via Geometry-Integrated Cycle-domain Denoising Diffusion Probabilistic Models

Yuan Gao, Shaoyan Pan, Mingzhe Hu +6

Cone-beam CT (CBCT) is widely used in clinical radiotherapy for image-guided treatment, improving setup accuracy, adaptive planning, and motion management. However, slow gantry rot…

physics.med-ph2025★ 2 cited

A Digital Twin Framework for Adaptive Treatment Planning in Radiotherapy

Chih-Wei Chang, Sri Sai Akkineni, Mingzhe Hu +7

The development of a digital twin (DT) framework for fast online adaptive proton therapy planning in prostate stereotactic body radiation therapy (SBRT) with dominant intraprostati…

cs.CV2025

A Large Convolutional Neural Network for Clinical Target and Multi-organ Segmentation in Gynecologic Brachytherapy with Multi-stage Learning

Mingzhe Hu, Yuan Gao, Yuheng Li +10

Purpose: Accurate segmentation of clinical target volumes (CTV) and organs-at-risk is crucial for optimizing gynecologic brachytherapy (GYN-BT) treatment planning. However, anatomi…

physics.med-ph2024

Patient-Specific CBCT Synthesis for Real-time Tumor Tracking in Surface-guided Radiotherapy

Shaoyan Pan, Vanessa Su, Junbo Peng +6

We present a new imaging system to support real-time tumor tracking for surface-guided radiotherapy (SGRT). SGRT uses optical surface imaging (OSI) to acquire real-time surface top…

physics.med-ph2024

Unsupervised Bayesian Generation of Synthetic CT from CBCT Using Patient-Specific Score-Based Prior

Junbo Peng, Yuan Gao, Chih-Wei Chang +7

Background: Cone-beam computed tomography (CBCT) scans, performed fractionally (e.g., daily or weekly), are widely utilized for patient alignment in the image-guided radiotherapy (…

eess.IV2023★ 1 cited

Liver Tumor Screening and Diagnosis in CT with Pixel-Lesion-Patient Network

Ke Yan, Xiaoli Yin, Yingda Xia +10

Liver tumor segmentation and classification are important tasks in computer aided diagnosis. We aim to address three problems: liver tumor screening and preliminary diagnosis in no…

physics.med-ph2022★ 12 cited

MRI-based Material Mass Density and Relative Stopping Power Estimation via Deep Learning for Proton Therapy

Yuan Gao, Chih-Wei Chang, Sagar Mandava +10

Magnetic Resonance Imaging (MRI) is increasingly incorporated into treatment planning, because of its superior soft tissue contrast used for tumor and soft tissue delineation versu…

physics.med-ph2022★ 16 cited

Multimodal Imaging-based Material Mass Density Estimation for Proton Therapy Using Physics-Constrained Deep Learning

Chih-Wei Chang, Raanan Marants, Yuan Gao +7

Mapping computed tomography (CT) number to material property dominates the proton range uncertainty. This work aims to develop a physics-constrained deep learning-based multimodal…