Showing 2025 · stat.MEShow all
3 papers · 2 filters
stat.ME2025
A Clustering Approach for Basket Trials Based on Treatment Response Trajectories
Masahiro Kojima, Keisuke Hanada, Atsuya Sato
Heterogeneity in efficacy is sometimes observed across baskets in basket trials. In this study, we propose a model-free clustering framework that groups baskets based on transition…
stat.ME2025
Sample size re-estimation in blinded hybrid-control design using inverse probability weighting
Masahiro Kojima, Shunichiro Orihara, Keisuke Hanada +1
With the increasing availability of data from historical studies and real-world data sources, hybrid control designs that incorporate external data into the evaluation of current s…
stat.ME2025
Integrate Meta-analysis into Specific Study (InMASS) for Estimating Conditional Average Treatment Effect
Keisuke Hanada, Masahiro Kojima
Randomized controlled trials are the standard method for estimating causal effects, ensuring sufficient statistical power and confidence through adequate sample sizes. However, ach…