most citedSparse autoencoders reveal organized biological knowledge but minimal regulatory logic in single-cell foundation models: a comparative atlas of Geneformer and scGPT

1 citations · 2 across the 10 of their papers we have counts for

collaborators

13 papers

cs.AI2026

A survey detection channel overrides the pixels in an astronomical foundation model, and biases tomographic mean redshifts

Ihor Kendiukhov

Foundation models for astronomy are trained on survey pixels together with the catalogue products derived from those pixels. Those catalogues are incomplete at a measurable rate, a…

cs.LG2026

Scaling Laws for Masked-Reconstruction Transformers on Single-Cell Transcriptomics

Ihor Kendiukhov

Neural scaling laws -- power-law relationships between loss, model size, and data -- have been extensively documented for language and vision transformers, yet their existence in s…

stat.CO2026

Ergodicity Library: A Python Toolkit for Stochastic-Process Simulation, Time-Average Diagnostics, and Agent-Based Experiments

Ihor Kendiukhov

ergodicity is an open-source Python library for computational work on stochastic dynamics, with particular emphasis on non-ergodicity, time-average behavior, heavy-tailed processes…

cs.LG2026

Exhaustive Circuit Mapping of a Single-Cell Foundation Model Reveals Massive Redundancy, Heavy-Tailed Hub Architecture, and Layer-Dependent Differentiation Control

Ihor Kendiukhov

Mechanistic interpretability of biological foundation models has relied on selective feature sampling, pairwise interaction testing, and observational trajectory analysis. Each of…

cs.LG2026

Discovery of a Hematopoietic Manifold in scGPT Yields a Method for Extracting Performant Algorithms from Biological Foundation Model Internals

Ihor Kendiukhov

We report the discovery and extraction of a compact hematopoietic algorithm from the single-cell foundation model scGPT, to our knowledge the first biologically useful, competitive…

q-bio.QM2026

What Topological and Geometric Structure Do Biological Foundation Models Learn? Evidence from 141 Hypotheses

Ihor Kendiukhov

When biological foundation models such as scGPT and Geneformer process single-cell gene expression, what geometric and topological structure forms in their internal representations…