4 papers
AMix-1: A Pathway to Test-Time Scalable Protein Foundation Model
Changze Lv, Jiang Zhou, Siyu Long +22
We introduce AMix-1, a powerful protein foundation model built on Bayesian Flow Networks and empowered by a systematic training methodology, encompassing pretraining scaling laws,…
ShortListing Model: A Streamlined SimplexDiffusion for Discrete Variable Generation
Yuxuan Song, Zhe Zhang, Yu Pei +7
Generative modeling of discrete variables is challenging yet crucial for applications in natural language processing and biological sequence design. We introduce the Shortlisting M…
Steering Protein Family Design through Profile Bayesian Flow
Jingjing Gong, Yu Pei, Siyu Long +7
Protein family design emerges as a promising alternative by combining the advantages of de novo protein design and mutation-based directed evolution.In this paper, we propose Profi…
A Periodic Bayesian Flow for Material Generation
Hanlin Wu, Yuxuan Song, Jingjing Gong +6
Generative modeling of crystal data distribution is an important yet challenging task due to the unique periodic physical symmetry of crystals. Diffusion-based methods have shown e…