3 papers
q-bio.BM2025
ProxelGen: Generating Proteins as 3D Densities
Felix Faltings, Hannes Stark, Regina Barzilay +1
We develop ProxelGen, a protein structure generative model that operates on 3D densities as opposed to the prevailing 3D point cloud representations. Representing proteins as voxel…
q-bio.BM2025
Protein FID: Improved Evaluation of Protein Structure Generative Models
Felix Faltings, Hannes Stark, Tommi Jaakkola +1
Protein structure generative models have seen a recent surge of interest, but meaningfully evaluating them computationally is an active area of research. While current metrics have…
q-bio.QM2025
Hierarchical protein backbone generation with latent and structure diffusion
Jason Yim, Marouane Jaakik, Ge Liu +5
We propose a hierarchical protein backbone generative model that separates coarse and fine-grained details. Our approach called LSD consists of two stages: sampling latents which a…