Showing 2026 · cs.LGShow all
3 papers · 2 filters
cs.LG2026
scCBGM: Interpretable Single-Cell Counterfactual Editing
Alma Andersson, Aya Abdelsalam Ismail, Edward De Brouwer +6
Understanding cellular phenotypes and how they respond to perturbations is critical for disease biology and therapeutic design. Single-cell RNA sequencing enables characterization…
cs.LG2026
Generate in Reconstruction Space, Match in Semantic Space: Transport Geometry for One-Step Generation
Hugues Van Assel, Edward De Brouwer, Saeed Saremi +2
Generative modeling and self-supervised representation learning (SSL) optimize structurally different objectives: generative training rewards distributional fidelity, while SSL rew…
cs.LG2026
AssayBench: An Assay-Level Virtual Cell Benchmark for LLMs and Agents
Edward De Brouwer, Carl Edwards, Alexander Wu +9
Recent advances in machine learning and large-scale biological data collections have revived the prospect of building a virtual cell, a computational model of cellular behavior tha…