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physics.med-ph2025
Simulation-based digital twinning of activation and repolarisation sequences from the ECG across healthy and diseased hearts
James A Coleman, Julia Camps, Abdallah I Hasaballa +1
Abnormal patterns of ventricular repolarisation contribute to lethal arrhythmias in various cardiac conditions, including inherited and acquired channelopathies, cardiomyopathies,…
physics.med-ph2023
Digital Twinning of the Human Ventricular Activation Sequence to Clinical 12-lead ECGs and Magnetic Resonance Imaging Using Realistic Purkinje Networks for in Silico Clinical Trials
Julia Camps, Lucas Arantes Berg, Zhinuo Jenny Wang +12
Cardiac in silico clinical trials can virtually assess the safety and efficacy of therapies using human-based modelling and simulation. These technologies can provide mechanistic e…