activity
20232026
most citedIntegrating Chain-of-Thought and Retrieval Augmented Generation Enhances Rare Disease Diagnosis from Clinical Notes

5 citations · 9 across the 10 of their papers we have counts for

collaborators

11 papers

eess.SY2026

Learning Stability of Replay-Based Co-Optimization for Transmission Expansion under Strategic Bidding

Tomonari Kanazawa, Hikaru Hoshino, Eiko Furutani

This paper investigates the behavior of learning-based co-optimization for transmission expansion under strategic bidding in electricity markets. In this framework, transmission ca…

cs.LG2026

Beyond Post-Hoc Temperature Scaling: Bilevel Optimization for LLM Calibration

Ruochen Jin, Zhanliang Wang, Zongyu Dai +2

Preference alignment often makes large language models (LLMs) overconfident and poorly calibrated. Traditional post-hoc temperature scaling is inherently domain-dependent: a temper…

cs.CL2026

A Semantic-Sampling Framework for Evaluating Calibration in Open-Ended Question Answering

Zhanliang Wang, Jiancong Xiao, Ruochen Jin +3

Calibration measures whether a model's predicted confidence aligns with its empirical accuracy, and is central to the reliable deployment of large language models (LLMs) in high-st…

cs.LG2026

Beyond Logit Adjustment: A Residual Decomposition Framework for Long-Tailed Reranking

Zhanliang Wang, Hongzhuo Chen, Quan Minh Nguyen +2

Long-tailed classification, where a small number of frequent classes dominate many rare ones, remains challenging because models systematically favor frequent classes at inference…

q-bio.QM2026

Autonomous Agent-Orchestrated Digital Twins (AADT): Leveraging the OpenClaw Framework for State Synchronization in Rare Genetic Disorders

Hongzhuo Chen, Zhanliang Wang, Quan M. Nguyen +3

Background: Medical Digital Twins (MDTs) are computational representations of individual patients that integrate clinical, genomic, and physiological data to support diagnosis, tre…

cs.AI2025

MultiSHAP: A Shapley-Based Framework for Explaining Cross-Modal Interactions in Multimodal AI Models

Zhanliang Wang, Kai Wang

Multimodal AI models have achieved impressive performance in tasks that require integrating information from multiple modalities, such as vision and language. However, their "black…

cs.LG2025

Fair CCA for Fair Representation Learning: An ADNI Study

Bojian Hou, Zhanliang Wang, Zhuoping Zhou +6

Canonical correlation analysis (CCA) is a technique for finding correlations between different data modalities and learning low-dimensional representations. As fairness becomes cru…

q-bio.QM2025

Multimodal Integrated Knowledge Transfer to Large Language Models through Preference Optimization with Biomedical Applications

Zhanliang Wang, Da Wu, Quan Nguyen +2

The scarcity of high-quality multimodal biomedical data limits the ability to effectively fine-tune pretrained Large Language Models (LLMs) for specialized biomedical tasks. To add…

cs.LG2025

Restoring Calibration for Aligned Large Language Models: A Calibration-Aware Fine-Tuning Approach

Jiancong Xiao, Bojian Hou, Zhanliang Wang +4

One of the key technologies for the success of Large Language Models (LLMs) is preference alignment. However, a notable side effect of preference alignment is poor calibration: whi…

cs.CL2025★ 5 cited

Integrating Chain-of-Thought and Retrieval Augmented Generation Enhances Rare Disease Diagnosis from Clinical Notes

Zhanliang Wang, Da Wu, Quan Nguyen +1

Background: Several studies show that large language models (LLMs) struggle with phenotype-driven gene prioritization for rare diseases. These studies typically use Human Phenotype…

q-bio.QM2023★ 4 cited

GestaltMML: Enhancing Rare Genetic Disease Diagnosis through Multimodal Machine Learning Combining Facial Images and Clinical Text

Da Wu, Zhanliang Wang, Hongzhuo Chen +12

Individuals with suspected rare genetic disorders often undergo multiple clinical evaluations, imaging studies, laboratory tests, and genetic tests over a prolonged period of time,…