activity
20242026
most citedReconstructing semi-directed level-1 networks using few quarnets

10 citations · 11 across the 8 of their papers we have counts for

collaborators

9 papers

q-bio.PE2026

Encoding level-3 semi-directed phylogenetic networks by quarnets and quinnets

Niels Holtgrefe, Katharina T. Huber, Leo van Iersel +1

Phylogenetic networks generalize phylogenetic trees as models of evolutionary history, allowing lineages to merge as well as to diverge. For many types of genetic data the root pos…

q-bio.PE2026

On Tree-Network Distinguishability and Full Identifiability of Phylogenetic Networks

Jari Brits, Niels Holtgrefe, Leo van Iersel +1

Phylogenetic networks generalize phylogenetic trees to evolutionary histories that include reticulate events such as recombination, horizontal gene transfer, and hybridization. Und…

cs.DS2026

Tractable Maximization of Budgeted Phylogenetic Diversity on Networks Utilizing Node Scanwidth

Niels Holtgrefe, Jannik Schestag

Background: Identifying a subset of taxa that maximizes phylogenetic diversity is a cornerstone of quantitative conservation planning. Traditionally, phylogenetic diversity is defi…

cs.CC2026

Limits of Kernelization and Parametrization for Phylogenetic Diversity with Dependencies

Niels Holtgrefe, Jannik Schestag, Norbert Zeh

In the Maximize Phylogenetic Diversity problem, we are given a phylogenetic tree that represents the genetic proximity of species, and we are asked to select a subset of species of…

q-bio.PE2025

Bounds on the sequence length sufficient to reconstruct binary level- phylogenetic networks under the CFN model

Martin Frohn, Niels Holtgrefe, Leo van Iersel +2

Phylogenetic trees and networks are graphs used to model evolutionary relationships, with trees representing strictly branching histories and networks allowing for events in which…

q-bio.PE2025

Characterizing semi-directed phylogenetic networks and their multi-rootable variants

Niels Holtgrefe, Katharina T. Huber, Leo van Iersel +2

In evolutionary biology, phylogenetic networks are graphs that provide a flexible framework for representing complex evolutionary histories that involve reticulate evolutionary eve…

q-bio.PE2025

Distinguishing Phylogenetic Level-2 Networks with Quartets and Inter-Taxon Quartet Distances

Niels Holtgrefe, Elizabeth S. Allman, Hector Baños +4

The inference of phylogenetic networks, which model complex evolutionary processes including hybridization and gene flow, remains a central challenge in evolutionary biology. Until…

q-bio.PE2024★ 10 cited

Reconstructing semi-directed level-1 networks using few quarnets

Martin Frohn, Niels Holtgrefe, Leo van Iersel +2

Semi-directed networks are partially directed graphs that model evolution where the directed edges represent reticulate evolutionary events. We present an algorithm that reconstruc…

cs.DS2024★ 1 cited

Exact and Heuristic Computation of the Scanwidth of Directed Acyclic Graphs

Niels Holtgrefe, Leo van Iersel, Mark Jones

To measure the tree-likeness of a directed acyclic graph (DAG), a new width parameter that considers the directions of the arcs was recently introduced: scanwidth. We present the f…