3 papers
stat.ME2025
A nonparametric approach to practical identifiability of nonlinear mixed effects models
Tyler Cassidy, Stuart T. Johnston, Michael Plank +4
Mathematical modelling is a widely used approach to understand and interpret clinical trial data. This modelling typically involves fitting mechanistic mathematical models to data…
stat.ME2025
A cautionary tale of model misspecification and identifiability
Alexander P Browning, Jennifer A Flegg, Ryan J Murphy
Mathematical models are routinely applied to interpret biological data, with common goals that include both prediction and parameter estimation. A challenge in mathematical biology…
q-bio.PE2025
Sunlight-heated refugia protect frogs from chytridiomycosis: a mathematical modelling study
Claire M. Miller, Michael J. Lydeamore, Lee Berger +4
The fungal disease Chytridiomycosis poses a threat to frog populations worldwide. It has driven over 90 amphibian species to extinction and severely affected hundreds more. Difficu…