3 papers
q-bio.SC2025
Kinesin-12 KLP-18 contributes to the kinetochore-microtubule poleward flux during the metaphase of C. elegans one-cell embryo
Nina Soler, Mathis Da Silva, Christophe Tascon +6
The mitotic spindle partitions chromosomes during cell division by connecting the poles to kinetochores through microtubules (MTs). Their plus-ends, facing the chromosomes, exhibit…
q-bio.SC2017
Dynein dynamics at the microtubule plus-ends and cortex during division in the C. zygote
Ruddi Rodriguez Garcia, Laurent Chesneau, Sylvain Pastezeur +3
During asymmetric cell division, dynein generates forces, which position the spindle to reflect polarity and ensure correct daughter cell fates. The transient cortical localization…
q-bio.SC2017
LET-99-dependent spatial restriction of active force generators makes spindle's position robust
Hélène Bouvrais, Laurent Chesneau, Sylvain Pastezeur +2
During the asymmetric division of the Caenorhabditis elegans nematode zygote, the polarity cues distribution and daughter cell fates depend on the correct positioning of the mitoti…