most citedBenchmarking Transcriptomics Foundation Models for Perturbation Analysis : one PCA still rules them all

11 citations · 13 across the 4 of their papers we have counts for

collaborators

5 papers

cs.LG2025

Conditional Chemical Language Models are Versatile Tools in Drug Discovery

Lu Zhu, Emmanuel Noutahi

Generative chemical language models (CLMs) have demonstrated strong capabilities in molecular design, yet their impact in drug discovery remains limited by the absence of reliable…

cs.LG2025

A Cross Modal Knowledge Distillation & Data Augmentation Recipe for Improving Transcriptomics Representations through Morphological Features

Ihab Bendidi, Yassir El Mesbahi, Alisandra K. Denton +4

Understanding cellular responses to stimuli is crucial for biological discovery and drug development. Transcriptomics provides interpretable, gene-level insights, while microscopy…

cs.LG20252 cited

TxPert: Leveraging Biochemical Relationships for Out-of-Distribution Transcriptomic Perturbation Prediction

Frederik Wenkel, Wilson Tu, Cassandra Masschelein +12

Accurately predicting cellular responses to genetic perturbations is essential for understanding disease mechanisms and designing effective therapies. Yet exhaustively exploring th…

cs.LG2025

Graph and Simplicial Complex Prediction Gaussian Process via the Hodgelet Representations

Mathieu Alain, So Takao, Xiaowen Dong +2

Predicting the labels of graph-structured data is crucial in scientific applications and is often achieved using graph neural networks (GNNs). However, when data is scarce, GNNs su…

cs.LG202411 cited

Benchmarking Transcriptomics Foundation Models for Perturbation Analysis : one PCA still rules them all

Ihab Bendidi, Shawn Whitfield, Kian Kenyon-Dean +4

Understanding the relationships among genes, compounds, and their interactions in living organisms remains limited due to technological constraints and the complexity of biological…