activity
20232026
most citedEvaluation of large language models for discovery of gene set function

92 citations · 92 across the 4 of their papers we have counts for

collaborators

5 papers

cs.CL2026

HypoEvolve: Genetic Algorithms Enable Multi-Agent LLMs to Discover Scientific Hypotheses

Jieyuan Liu, Mengzhou Hu, Jefferson Chen +10

Scientific agents contribute to hypothesis discovery by synthesizing evidence, assessing proposals, and developing new explanations. Recent systems combine scientific agents with e…

q-bio.GN2026

CellMaster: Collaborative Cell Type Annotation in Single-Cell Analysis

Zhen Wang, Yiming Gao, Jieyuan Liu +10

Single-cell RNA-seq (scRNA-seq) enables atlas-scale profiling of complex tissues, revealing rare lineages and transient states. Yet, assigning biologically valid cell identities re…

cs.LG2025

Benchmarking and Evaluation of AI Models in Biology: Outcomes and Recommendations from the CZI Virtual Cells Workshop

Elizabeth Fahsbender, Alma Andersson, Jeremy Ash +32

Artificial intelligence holds immense promise for transforming biology, yet a lack of standardized, cross domain, benchmarks undermines our ability to build robust, trustworthy mod…

cs.CY2025

Bridge2AI: Building A Cross-disciplinary Curriculum Towards AI-Enhanced Biomedical and Clinical Care

John Rincon, Alexander R. Pelletier, Destiny Gilliland +16

Objective: As AI becomes increasingly central to healthcare, there is a pressing need for bioinformatics and biomedical training systems that are personalized and adaptable. Materi…

q-bio.GN2023★ 92 cited

Evaluation of large language models for discovery of gene set function

Mengzhou Hu, Sahar Alkhairy, Ingoo Lee +6

Gene set analysis is a mainstay of functional genomics, but it relies on curated databases of gene functions that are incomplete. Here we evaluate five Large Language Models (LLMs)…