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cs.LG2026
Chreode: A Cell World Model for One-Step Temporal Dynamics and Perturbation Prediction
Mufan Qiu, Genhui Zheng, Yinuo Xu +4
Predicting how a cell will change its transcriptional state under a developmental signal or a genetic perturbation is the computational core of in-silico biology and the AI Virtual…
cs.LG2025
GRNFormer: A Biologically-Guided Framework for Integrating Gene Regulatory Networks into RNA Foundation Models
Mufan Qiu, Xinyu Hu, Fengwei Zhan +6
Foundation models for single-cell RNA sequencing (scRNA-seq) have shown promising capabilities in capturing gene expression patterns. However, current approaches face critical limi…