4 papers
Studying Competing Events with Federated Cumulative Incidence Curves
Malcolm Risk, Shuang Yang, Jiang Bian +6
Combining electronic health record (EHR) data from multiple institutions is a valuable strategy for conducting post-market safety surveillance of medical products, but privacy conc…
Privacy-preserving causal mediation analysis using distributed electronic health record networks
Hyojung Jang, Rotana Radwan, Malcolm Risk +5
Electronic health record (EHR) networks provide unprecedented opportunities to study treatment mechanisms at scale, but mediation analyses across institutions are often hindered by…
Distributed Kaplan-Meier Analysis via the Influence Function with Application to COVID-19 and COVID-19 Vaccine Adverse Events
Malcolm Risk, Xu Shi, Lili Zhao
During the COVID-19 pandemic, regulatory decision-making was hampered by a lack of timely and high-quality data on rare outcomes. Studying rare outcomes following infection and vac…
Time-to-Event Modeling with Pseudo-Observations in Federated Settings
Hyojung Jang, Malcolm Risk, Yaojie Wang +3
In multi-center clinical research, privacy regulations often prohibit pooling individual-level records, complicating the analysis of time-to-event data. Current federated survival…