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stat.AP2024
Comparative Effectiveness Research with Average Hazard for Censored Time-to-Event Outcomes: A Numerical Study
Hong Xiong, Jean Connors, Deb Schrag +1
The average hazard (AH), recently introduced by Uno and Horiguchi, represents a novel summary metric of event time distributions, conceptualized as the general censoring-free avera…
stat.ME2024★ 1 cited
A Novel Stratified Analysis Method for Testing and Estimating Overall Treatment Effects on Time-to-Event Outcomes Using Average Hazard with Survival Weight
Zihan Qian, Lu Tian, Miki Horiguchi +1
Given the limitations of using the Cox hazard ratio to summarize the magnitude of the treatment effect, alternative measures that do not have these limitations are gaining attentio…
stat.ME2024
Assessing Delayed Treatment Benefits of Immunotherapy Using Long-Term Average Hazard: A Novel Test/Estimation Approach
Miki Horiguchi, Lu Tian, Kenneth L. Kehl +1
Delayed treatment effects on time-to-event outcomes have often been observed in randomized controlled studies of cancer immunotherapies. In the case of delayed onset of treatment e…