2 citations · 3 across the 7 of their papers we have counts for
3 papers · 1 filter
Co-optimization of codon usage and mRNA secondary structure using quantum computing
Dimitris Alevras, Mihir Metkar, Triet Friedhoff +5
Co-optimizing mRNA sequences for both codon optimality and secondary structure is crucial for producing stable and efficacious mRNA therapeutics. Codon optimization, which adjusts…
Towards secondary structure prediction of longer mRNA sequences using a quantum-centric optimization scheme
Vaibhaw Kumar, Dimitris Alevras, Mihir Metkar +9
Accurate prediction of mRNA secondary structure is critical for understanding gene expression, translation efficiency, and advancing mRNA-based therapeutics. However, the combinato…
mRNA Folding Algorithms for Structure and Codon Optimization
Max Ward, Mary Richardson, Mihir Metkar
mRNA technology has revolutionized vaccine development, protein replacement therapies, and cancer immunotherapies, offering rapid production and precise control over sequence and e…