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stat.AP2024
Bayesian Perspective for Orientation Determination in Cryo-EM with Application to Structural Heterogeneity Analysis
Sheng Xu, Amnon Balanov, Amit Singer +1
Accurate orientation estimation is a crucial component of 3D molecular structure reconstruction, both in single-particle cryo-electron microscopy (cryo-EM) and in the increasingly…
math.NA2024
Subspace method of moments for ab initio 3-D single-particle cryo-EM reconstruction
Jeremy Hoskins, Yuehaw Khoo, Oscar Mickelin +2
Cryo-electron microscopy (cryo-EM) is a widely used technique for recovering the 3-D structure of biological molecules from a large number of experimentally generated noisy 2-D tom…