3 papers
cs.LG2026
Disease Is a Spectral Perturbation
John D. Mayfield, Matthew S. Rosen
We propose a novel method of understanding disease transformation from a healthy baseline with biomarker-level explainability. By modeling the biomarker covariance matrices of heal…
q-bio.OT2025
Frequency-Domain Analysis of Time-Dependent Multiomic Data in Progressive Neurodegenerative Diseases: A Proposed Quantum-Classical Hybrid Approach with Quaternionic Extensions
John D. Mayfield
Progressive neurodegenerative diseases, including Alzheimer's disease (AD), multiple sclerosis (MS), Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS), exhibit comp…
cs.LG2024
Evaluation of QCNN-LSTM for Disability Forecasting in Multiple Sclerosis Using Sequential Multisequence MRI
John D. Mayfield, Issam El Naqa
Introduction Quantum Convolutional Neural Network (QCNN)-Long Short-Term Memory (LSTM) models were studied to provide sequential relationships for each timepoint in MRIs of patient…