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stat.ME2026
Communicating results in trials with multiple hypotheses or adaptive design features
Elina Asikanius, Marcel Wolbers, Mouna Akacha +8
Over time, clinical trials have increasingly incorporated complex design and analysis elements such as interim analyses, adaptations, multiple endpoints, and sophisticated multipli…
stat.ME2024
Simplifying Causal Mediation Analysis for Time-to-Event Outcomes using Pseudo-Values
Alex Ocampo, Enrico Giudice, Dieter A. Häring +3
Mediation analysis for survival outcomes is challenging. Most existing methods quantify the treatment effect using the hazard ratio (HR) and attempt to decompose the HR into the di…