5 papers
Myelin Distribution at the Optic Nerve Myelination Transition Zone Influences Axonal Biomechanics
Tingting Liu, Xiaofei Wang, C. Ross Ethier +3
Purpose: The lamina cribrosa (LC) is considered the initial site of glaucomatous retinal ganglion cell (RGC) injury, and is also the region where unmyelinated RGC axons become myel…
Fusing Structural Phenotypes with Functional Data for Early Prediction of Primary Angle Closure Glaucoma Progression
Swati Sharma, Thanadet Chuangsuwanich, Royston K. Y. Tan +7
Purpose: To classify eyes as slow or fast glaucoma progressors in patients with primary angle closure glaucoma (PACG) using an integrated approach combining optic nerve head (ONH)…
AI to Identify Strain-sensitive Regions of the Optic Nerve Head Linked to Functional Loss in Glaucoma
Thanadet Chuangsuwanich, Monisha E. Nongpiur, Fabian A. Braeu +8
Objective: (1) To assess whether ONH biomechanics improves prediction of three progressive visual field loss patterns in glaucoma; (2) to use explainable AI to identify strain-sens…
3D Structural Phenotype of the Optic Nerve Head at the Intersection of Glaucoma and Myopia -- A Key to Improving Glaucoma Diagnosis in Myopic Populations
Swati Sharma, Fabian A. Braeu, Thanadet Chuangsuwanich +9
Purpose: To characterize the 3D structural phenotypes of the optic nerve head (ONH) in patients with glaucoma, high myopia, and concurrent high myopia and glaucoma, and to evaluate…
Introducing the Biomechanics-Function Relationship in Glaucoma: Improved Visual Field Loss Predictions from intraocular pressure-induced Neural Tissue Strains
Thanadet Chuangsuwanich, Monisha E. Nongpiur, Fabian A. Braeu +8
Objective. (1) To assess whether neural tissue structure and biomechanics could predict functional loss in glaucoma; (2) To evaluate the importance of biomechanics in making such p…