6 papers
A Novel Vascular Risk Scoring Framework for Quantifying Sex-Specific Cerebral Perfusion from 3D pCASL MRI
Sneha Noble, Neelam Sinha, Vaanathi Sundareshan +1
The influence of sex and age on cerebral perfusion is recognized, but the specific impacts on regional cerebral blood flow (CBF) and vascular risk remain to be fully characterized.…
Alzheimer's Disease Classification Using Retinal OCT: TransnetOCT and Swin Transformer Models
Siva Manohar Reddy Kesu, Neelam Sinha, Hariharan Ramasangu +1
Retinal optical coherence tomography (OCT) images are the biomarkers for neurodegenerative diseases, which are rising in prevalence. Early detection of Alzheimer's disease using re…
Leveraging Persistent Homology for Differential Diagnosis of Mild Cognitive Impairment
Ninad Aithal, Debanjali Bhattacharya, Neelam Sinha +1
Mild cognitive impairment (MCI) is characterized by subtle changes in cognitive functions, often associated with disruptions in brain connectivity. The present study introduces a n…
Bayesian Network Modeling of Causal Influence within Cognitive Domains and Clinical Dementia Severity Ratings for Western and Indian Cohorts
Wupadrasta Santosh Kumar, Sayali Rajendra Bhutare, Neelam Sinha +1
This study investigates the causal relationships between Clinical Dementia Ratings (CDR) and its six domain scores across two distinct aging datasets: the Alzheimer's Disease Neuro…
Heart Rate and its Variability from Short-term ECG Recordings as Biomarkers for Detecting Mild Cognitive Impairment in Indian Population
Anjo Xavier, Sneha Noble, Justin Joseph +1
Alterations in Heart Rate (HR) and Heart Rate Variability (HRV) can reflect autonomic dysfunction associated with neurodegeneration. We investigate the influence of Mild Cognitive…
Classification of Alzheimer's Dementia vs. Healthy subjects by studying structural disparities in fMRI Time-Series of DMN
Sneha Noble, Chakka Sai Pradeep, Neelam Sinha +1
Time series from different regions of interest (ROI) of default mode network (DMN) from Functional Magnetic Resonance Imaging (fMRI) can reveal significant differences between heal…