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20242026
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physics.med-ph2026

NGSE-Corr: A technique for objective clinical evaluation of quantitative-imaging methods without a gold standard

Yan Liu, Ziping Liu, Zekun Li +4

Objective evaluation of quantitative-imaging (QI) methods based on how reliably they measure true values is important for clinical translation. Performing such evaluation with pati…

physics.med-ph2026

Extending Regression Without Truth to Integrate Ground-Truth Measurements for Evaluating Quantitative Imaging Methods with Patient Data

Yan Liu, Abhinav K. Jha

Objective evaluation of quantitative imaging (QI) methods with patient data is often hindered by the lack of gold standards. To address this challenge, a class of regression-withou…

physics.med-ph2026

Comparing evaluation of quantitative imaging methods using reference standards vs. regression-without-truth-based technique

Yan Liu, Abhinav K. Jha

Clinical translation of quantitative imaging (QI) methods requires objective evaluation of these methods on reliably measuring the underlying true quantitative values. Ideally, suc…

physics.med-ph2025

Objective Task-based Evaluation of Quantitative Medical Imaging Methods: Emerging Frameworks and Future Directions

Yan Liu, Huitian Xia, Nancy A. Obuchowski +4

Quantitative imaging (QI) is demonstrating strong promise across multiple clinical applications. For clinical translation of QI methods, objective evaluation on clinically relevant…

physics.med-ph2024

How accurately can quantitative imaging methods be ranked without ground truth: An upper bound on no-gold-standard evaluation

Yan Liu, Abhinav K. Jha

Objective evaluation of quantitative imaging (QI) methods with patient data, while important, is typically hindered by the lack of gold standards. To address this challenge, no-gol…