Stress-testing cross-cancer generalizability of 3D nnU-Net for PET-CT tumor segmentation: multi-cohort evaluation with novel oesophageal and lung cancer datasets

Soumen Ghosh, Christine Jestin Hannan, Rajat Vashistha +8

Robust generalization is essential for deploying deep learning based tumor segmentation in clinical PET-CT workflows, where anatomical sites, scanners, and patient populations vary…