3 papers
q-bio.NC2025
Correcting model error bias in estimations of neuronal dynamics from time series observations
Ian Williams, Joseph D. Taylor, Alain Nogaret
Neuron models built from experimental data have successfully predicted observed voltage oscillations within and beyond training range. A tantalising prospect is the possibility of…
q-bio.QM2023
Inferring the dynamics of ionic currents from recursive piecewise data assimilation of approximate neuron models
Stephen A. Wells, Joseph D. Taylor, Paul G. Morris +1
We construct neuron models from data by transferring information from an observed time series to the state variables and parameters of Hodgkin-Huxley models. When the learning peri…
q-bio.QM2023
Single shot diagnosis of ion channel dysfunction from assimilation of cell membrane dynamics
Paul G Morris, Joseph D. Taylor, Julian F. R. Paton +1
Many neurological diseases originate in the dysfunction of cellular ion channels. Their diagnosis presents a challenge especially when alterations in the complement of ion channels…