2 citations · 2 across the 4 of their papers we have counts for
4 papers
Unraveling the Redox Mechanisms Underlying FLASH Radiotherapy: Critical Dose Thresholds and NRF2-Driven Tissue Sparing
Yan Zhang, Chenyang Huang, Ankang Hu +10
FLASH radiotherapy (FLASH-RT) achieves tumor control comparable to conventional dose-rate irradiation (CONV-RT) while significantly reducing radiation damage to normal tissues. How…
Impact of Oxygen on DNA Damage Distribution in 3D Genome and its Correlation to Oxygen Enhancement Ratio after High-LET Irradiation
Ankang Hu, Wanyi Zhou, Xiyu Luo +2
The variation of the oxygen enhancement ratio (OER) across linear energy transfer (LET) currently lacks a comprehensive mechanistic interpretation and a mechanistic model. Our earl…
Correlation Between DNA Double-Strand Break Distribution in 3D Genome and Radiation-Induced Cell Death
Ankang Hu, Wanyi Zhou, Xiyu Luo +2
The target theory is the most classical hypothesis explaining radiation-induced cell death, the physical or biological nature of the "target" remains ambiguous. This study hypothes…
Influencing Factors of the FLASH Effect: Unveiling the Importance of Free Radicals
Yan Zhang, Chenyang Huang, Ankang Hu +10
Purpose: Our aim was to elucidate the critical factors responsible for inducing the FLASH effect, focusing on the role of free radicals through simulation and experimental approach…