37 citations · 37 across the 5 of their papers we have counts for
6 papers
The Trajectory Statistics of Biological Exploratory Dynamics
Sara D. Mahdavi, Gabriel L. Salmon, Minakshi Ashok +4
Biological processes, from molecules diffusing to their regulatory destinations to whales pursuing food or mates, are widely exploratory. Such behaviors are effective when some ver…
Informational blueprints reveal condition-dependent gene regulatory architectures
Doruk Efe Gökmen, Rosalind Wenshan Pan, Tom Röschinger +4
While coding regions in the genome have a direct interpretation in terms of protein products, significant fractions are non-coding and yet control essential biological functions. U…
Bifurcations and multistability in inducible three-gene toggle switch networks
Rebecca J. Rousseau, Rob Phillips
Control of transcription presides over a vast array of biological processes, including those mediated by gene regulatory circuits that exhibit multistability. Within these circuits…
The Environment-Dependent Regulatory Landscape of the E. coli Genome
Tom Röschinger, Heun Jin Lee, Rosalind Wenshan Pan +7
All cells respond to changes in both their internal milieu and the environment around them through the regulation of their genes. Despite decades of effort, there remain huge gaps…
Deciphering regulatory architectures from synthetic single-cell expression patterns
Rosalind Wenshan Pan, Tom Roeschinger, Kian Faizi +2
For the vast majority of genes in sequenced genomes, there is limited understanding of how they are regulated. Without such knowledge, it is not possible to perform a quantitative…
Reconciling Kinetic and Equilibrium Models of Bacterial Transcription
Muir J. Morrison, Manuel Razo-Mejia, Rob Phillips
The study of transcription remains one of the centerpieces of modern biology with implications in settings from development to metabolism to evolution to disease. Precision measure…