3 papers
stat.ME2026
Estimating the Wasserstein barycenter of one-dimensional distributions under sparse sampling
James Peng, Florian Stijven, Linbo Wang +1
We study distributional data under sparse sampling where each unit is represented by a probability distribution on the real line observed only through a small i.i.d.~sample. A natu…
stat.ME2025
Evaluation of Surrogate Endpoints Based on Meta-Analysis with Surrogate Indices
Florian Stijven, Peter B. Gilbert
The meta-analytic (MA) framework is the gold standard for evaluating putative surrogate endpoints but it is not well-suited for complex surrogates. We address this limitation by co…
stat.ME2024
A Reflection on the Impact of Misspecifying Unidentifiable Causal Inference Models in Surrogate Endpoint Evaluation
Gokce Deliorman, Florian Stijven, Wim Van der Elst +2
Surrogate endpoints are often used in place of expensive, delayed, or rare true endpoints in clinical trials. However, regulatory authorities require thorough evaluation to accept…