38 citations · 59 across the 7 of their papers we have counts for
7 papers
Nanoscale Protein Diffusion in Supercooled Cryoprotectant Solutions
Maddalena Bin, Anita Girelli, Mariia Filianina +15
Vitrification during cryopreservation requires a quantitative understanding of protein transport in deeply supercooled cryoprotectant solutions, yet direct measurements at molecula…
Depletion-Induced Interactions Modulate Nanoscale Protein Diffusion in Polymeric Crowder Solutions
Michelle Dargasz, Nimmi Das Anthuparambil, Sebastian Retzbach +26
Macromolecular crowding plays a crucial role in modulating protein dynamics in cellular and in vitro environments. Polymeric crowders such as dextran and Ficoll are known to induce…
Softness and Hydrodynamic Interactions Regulate Lipoprotein Transport in Crowded Yolk Environments
Nimmi Das Anthuparambil, Michelle Dargasz, Sonja Timmermann +27
Low-density lipoproteins (LDLs) serve as nutrient reservoirs in egg yolk for embryonic development and as promising drug carriers. Both roles critically depend on their mobility in…
Coherent X-rays reveal anomalous molecular diffusion and cage effects in crowded protein solutions
Anita Girelli, Maddalena Bin, Mariia Filianina +38
Understanding protein motion within the cell is crucial for predicting reaction rates and macromolecular transport in the cytoplasm. A key question is how crowded environments affe…
Nanocrystallites Modulate Intermolecular Interactions in Cryoprotected Protein Solutions
Mariia Filianina, Maddalena Bin, Sharon Berkowicz +7
Studying protein interactions at low temperatures has important implications for optimizing cryostorage processes of biological tissue, food, and protein-based drugs. One of the ma…
Coherent X-ray Scattering Reveals Nanoscale Fluctuations in Hydrated Proteins
Maddalena Bin, Mario Reiser, Mariia Filianina +15
Hydrated proteins undergo a transition in the deeply supercooled regime, which is attributed to rapid changes in hydration water and protein structural dynamics. Here, we investiga…
Resolving molecular diffusion and aggregation of antibody proteins with megahertz X-ray free-electron laser pulses
Mario Reiser, Anita Girelli, Anastasia Ragulskaya +26
X-ray free-electron lasers (XFELs) with megahertz repetition rate can provide novel insights into structural dynamics of biological macromolecule solutions. However, very high dose…