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q-bio.QM2025
HypoGeneAgent: A Hypothesis Language Agent for Gene-Set Cluster Resolution Selection Using Perturb-seq Datasets
Ying Yuan, Xing-Yue Monica Ge, Aaron Archer Waterman +8
Large-scale single-cell and Perturb-seq investigations routinely involve clustering cells and subsequently annotating each cluster with Gene-Ontology (GO) terms to elucidate the un…
cs.AI2025
Contextualizing biological perturbation experiments through language
Menghua Wu, Russell Littman, Jacob Levine +4
High-content perturbation experiments allow scientists to probe biomolecular systems at unprecedented resolution, but experimental and analysis costs pose significant barriers to w…