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physics.bio-ph2024
Emergent cell migration from cell shape deformations and T1 transitions
Harish P. Jain, Richard D. J. G. Ho, Luiza Angheluta
T1 transitions, which are localised cell rearrangements, play an important role in the fluidization of epithelial monolayers. Using a multi-phase field model and an active elastic…
physics.bio-ph2024
Role of tissue fluidization and topological defects in epithelial tubulogenesis
Richard D. J. G. Ho, Stig Ove Bøe, Dag Kristian Dysthe +1
Cellular rearrangements, as primary sources of tissue fluidization, facilitate topological transitions during tissue morphogenesis. We study the role of intrinsic cell properties s…