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physics.bio-ph2025
Spontaneous elongation of 3D gastruloids from local cell polarity alignment
Richard D. J. G. Ho, Endre J. L. Mossige, Sergei Ponomartcev +6
Gastruloids are 3D stem cell aggregate models for early embryogenesis that provide a unique platform to study how collective cell dynamics drive tissue symmetry breaking and axial…
physics.bio-ph2024
Emergent cell migration from cell shape deformations and T1 transitions
Harish P. Jain, Richard D. J. G. Ho, Luiza Angheluta
T1 transitions, which are localised cell rearrangements, play an important role in the fluidization of epithelial monolayers. Using a multi-phase field model and an active elastic…