6 papers
Eligibility-Aware Evidence Synthesis: An Agentic Framework for Clinical Trial Meta-Analysis
Yao Zhao, Zhiyue Zhang, Yanxun Xu
Clinical evidence synthesis requires identifying relevant trials from large registries and aggregating results that account for population differences. While recent LLM-based appro…
KM-GPT: An Automated Pipeline for Reconstructing Individual Patient Data from Kaplan-Meier Plots
Yao Zhao, Haoyue Sun, Yantian Ding +1
Reconstructing individual patient data (IPD) from Kaplan-Meier (KM) plots provides valuable insights for evidence synthesis in clinical research. However, existing approaches often…
LMAR: Language Model Augmented Retriever for Domain-specific Knowledge Indexing
Yao Zhao, Yantian Ding, Zhiyue Zhang +2
Retrieval Augmented Generation (RAG) systems often struggle with domain-specific knowledge due to performance deterioration of pre-trained embeddings and prohibitive computational…
TransformerLSR: Attentive Joint Model of Longitudinal Data, Survival, and Recurrent Events with Concurrent Latent Structure
Zhiyue Zhang, Yao Zhao, Yanxun Xu
In applications such as biomedical studies, epidemiology, and social sciences, recurrent events often co-occur with longitudinal measurements and a terminal event, such as death. T…
MoMA: Model-based Mirror Ascent for Offline Reinforcement Learning
Mao Hong, Zhiyue Zhang, Yue Wu +1
Model-based offline reinforcement learning methods (RL) have achieved state-of-the-art performance in many decision-making problems thanks to their sample efficiency and generaliza…
A high-order local discontinuous Galerkin method for the -Laplace equation
Yue Wu, Yan Xu
We study the high-order local discontinuous Galerkin (LDG) method for the -Laplace equation. We reformulate our spatial discretization as an equivalent convex minimization probl…