8 papers
MindVLM: Neural-Grounded Visual Captioning via Subject-Aware Semantic Evidence Selection
Zixiang Yin, Yu-Ping Wang, Zhengming Ding
Translating visual brain activity into natural language offers a powerful window into human cognition and neural semantic representation. Most prior brain-captioning approaches pro…
Explainability from Training with Applications to TCR-Epitope Prediction
Jiarui Li, Zixiang Yin, Samuel Landry +2
Deep learning models have achieved strong performance in artificial intelligence for science, yet their black-box nature limits our understanding of how they learn scientific tasks…
Structure-Regularized Interpretable TCR-Epitope Prediction
Jiarui Li, Zixiang Yin, Yunbei Zhang +4
T cell receptor (TCR)-epitope binding prediction is essential for understanding adaptive immunity and developing immunotherapies. Existing sequence- and structure-based models ofte…
Why Does It Look There? Structured Explanations for Image Classification
Jiarui Li, Zixiang Yin, Samuel J Landry +2
Deep learning models achieve remarkable predictive performance, yet their black-box nature limits transparency and trustworthiness. Although numerous explainable artificial intelli…
TCR-EML: Explainable Model Layers for TCR-pMHC Prediction
Jiarui Li, Zixiang Yin, Zhengming Ding +2
T cell receptor (TCR) recognition of peptide-MHC (pMHC) complexes is a central component of adaptive immunity, with implications for vaccine design, cancer immunotherapy, and autoi…
MIND: Insightful Multi-subject Invariant Neural Decoding
Zixiang Yin, Jiarui Li, Zhengming Ding
Decoding visual signals holds the tantalizing potential to unravel the complexities of cognition and perception. While recent studies have focused on reconstructing visual stimuli…
Rational Multi-Modal Transformers for TCR-pMHC Prediction
Jiarui Li, Zixiang Yin, Zhengming Ding +2
T cell receptor (TCR) recognition of peptide-MHC (pMHC) complexes is fundamental to adaptive immunity and central to the development of T cell-based immunotherapies. While transfor…
Quantifying Cross-Attention Interaction in Transformers for Interpreting TCR-pMHC Binding
Jiarui Li, Zixiang Yin, Haley Smith +3
CD8+ "killer" T cells and CD4+ "helper" T cells play a central role in the adaptive immune system by recognizing antigens presented by Major Histocompatibility Complex (pMHC) molec…