78 citations · 169 across the 10 of their papers we have counts for
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q-bio.MN2016★ 31 cited
Understanding the functional impact of copy number alterations in breast cancer using a network modeling approach
Sriganesh Srihari, Murugan Kalimutho, Samir Lal +5
Copy number alterations (CNAs) are thought to account for 85% of the variation in gene expression observed among breast tumours. The expression of cis-associated genes is impacted…
q-bio.MN2015★ 78 cited
Inferring synthetic lethal interactions from mutual exclusivity of genetic events in cancer
Sriganesh Srihari, Jitin Singla, Limsoon Wong +1
Background: Synthetic lethality (SL) refers to the genetic interaction between two or more genes where only their co-alteration (e.g. by mutations, amplifications or deletions) res…