3 papers
stat.ME2025
Evaluating treatment effects on longitudinal outcomes with attrition due to death: Methods for a two-dimentional estimand with a case study in Quality of Life
Dries Reynders, Doranne Thomassen, Satrajit Roychoudhury +5
When longitudinal outcomes are evaluated in mortal populations, their non-existence after death complicates the analysis and its causal interpretation. Where popular methods often…
stat.ME2025
The fundamental problem of risk prediction for individuals: health AI, uncertainty, and personalized medicine
Lasai Barreñada, Ewout W Steyerberg, Dirk Timmerman +3
Background and Objective: Clinical prediction models are commonly evaluated regarding performance for a population, although decisions are made for individuals. The classic view re…
stat.ME2023
Effective sample size: a measure of individual uncertainty in predictions
Doranne Thomassen, Saskia le Cessie, Hans van Houwelingen +1
Clinical prediction models are estimated using a sample of limited size from the target population, leading to uncertainty in predictions, even when the model is correctly specifie…