2 papers
math.PR2025
Parameter Estimation in Recurrent Tumor Evolution with Finite Carrying Capacity
Kevin Leder, Zicheng Wang, Xuanming Zhang
In this work, we investigate the population dynamics of tumor cells under therapeutic pressure. Although drug treatment initially induces a reduction in tumor burden, treatment fai…
stat.AP2024
Parameter Estimation from Single Patient, Single Time-Point Sequencing Data of Recurrent Tumors
Kevin Leder, Ruping Sun, Zicheng Wang +1
In this study, we develop consistent estimators for key parameters that govern the dynamics of tumor cell populations when subjected to pharmacological treatments. While these trea…